Dharmasena is a surname. Notable people with the surname include:
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Kumar Dharmasena (born 1971), Sri Lankan cricketer and umpire
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Samararatne Dharmasena (1950–2007), Sri Lankan sprinter
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Suranjith Dharmasena (born 1965), Sri Lankan cricketer
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W. H. M. Dharmasena (born 1955), Sri Lankan politician
{{surname
Sinhalese surnames